Maryland vs. Michigan State odds, prediction: 2026 Big Ten Conference men's college basketball picks from proven model

The 10th-ranked Michigan State Spartans will look to win their sixth game in a row when they battle the Maryland Terrapins in Big Ten Conference action on Saturday. Maryland is coming off an 89-70 loss at Illinois on Wednesday, while Michigan State downed Oregon 68-52 on Tuesday. The Terrapins (8-11, 1-7 Big Ten), who are 0-6 against ranked opponents, are 1-5 on the road this season. The Spartans (17-2, 7-1 Big Ten), who are tied for second in the conference, are 10-1 on their home court.

Tipoff from Breslin Center in East Lansing, Mich., is set for noon ET on CBS and Paramount+, which is also the new home to UFC. Plans start at $8.99/month and you can sign up here. 

Michigan State leads the all-time series 17-8, including a 6-2 edge in games played at East Lansing. Michigan State is an 18.5-point favorite in the latest Maryland vs. Michigan State odds from DraftKings Sportsbook, while the over/under for total points scored is 140.5. 

Before making any Maryland vs. Michigan State picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 12 on a sizzling 10-1 run on top-ranked over/under picks. Anyone following could have seen HUGE returns!

The model has simulated Maryland vs. Michigan State 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits in nearly 70% of simulations!

So who wins Maryland vs. Michigan State, and which side hits nearly 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!