The Marshall Thundering Herd go on the road to take on the Appalachian State Mountaineers. The Thundering Herd are coming off their first loss of the year, falling to East Carolina. Appalachian State blew out Elon, improving to 2-1. The Mountaineers are favored by seven points in the latest odds from Caesars Sportsbook, while the Over-Under is set at 58.5 points. Kickoff from Boone, N.C., is set for 7:30 p.m. ET. 

Before you make any Marshall vs. Appalachian State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Marshall vs. Appalachian State 10,000 times and the results are in. We can tell you that the model is leaning Under the total, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks. 

So who wins Marshall vs. Appalachian State? And which side of the spread hits almost 60 percent of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.