Marlins vs. Brewers odds, line, start time, picks, best bets for Friday, July 25, matchup from proven model

A pair of red-hot teams clash when the Miami Marlins take on the Milwaukee Brewers in a key National League matchup on Friday. The Marlins (48-53), who are third in the NL East, are 24-24 on the road this season. The Brewers (61-41), who lead the NL Central, are 33-17 on their home field in 2025.

First pitch from American Family Field in Milwaukee is set for 4:10 p.m. ET. The Brewers have won three of the last four meetings with the Marlins. Milwaukee is a -223 favorite on the money line (risk $223 to win $100) in the latest Marlins vs. Brewers odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 8 in the latest MLB odds.  

Before you make any Marlins vs. Brewers picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 17 of the 2025 MLB season 46-43 on top-rated MLB picks. It has excelled making home run prop picks this season, returning more than 40 units of profit. Anybody following could have seen strong returns!

The model has simulated Marlins vs. Brewers 10,000 times and the results are in. We can tell you the model is going Under on the run total, and it also says one side of the money line has all the value!

Who wins Marlins vs. Brewers, and which side of the money line has all the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 46-43 roll on top-rated MLB picks!