Mariners vs. Nationals odds, picks: Advanced computer MLB model releases selections for Wednesday matchup

The Washington Nationals and Seattle Mariners wrap up a quick, two-game series in the nation's capital at 12:05 p.m. ET on Wednesday. Washington is listed as a -115 favorite (risk $115 to win $100) at Caesars Sportsbook, while the Over-Under is set at 9 (see up-to-date odds for every game this week on our MLB odds page). Before making any Mariners vs. Nationals picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 275-236 on top-rated MLB money-line picks since the start of the 2021 season, returning over $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

The model knows the Mariners are red-hot right now. Seattle is 16-3 in the last 19 games, playing at a sky-high level. The Mariners are in the top three of the American League in walks, with above-average marks in triples, on-base percentage, and OPS. Seattle rookie phenom Julio Rodriguez leads the AL in stolen bases, and he is playing at a star level at the age of 21.

The model also knows the Nationals have clear offensive strengths. Washington leads the National League with only 634 strikeouts this season. The Nationals are also in the top five of the league in both hits and doubles, with above-average marks in batting average and on-base percentage among NL teams. Two-time All-Star Juan Soto leads the way with an NL-leading 73 walks and plenty of power.

Now, it has set its sights on Mariners vs. Nationals. We can tell you the model is leaning under the total, and it also says one team has all the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Who wins Mariners vs. Nationals? And which team has all the value on the money line? ... Join SportsLine right now to find out which side of the Mariners vs. Nationals matchup you should be all over Wednesday, all from the model on a roll on MLB picks!