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Mariners vs. Blue Jays odds, line, start time, picks, best bets for ALCS Game 2 matchup from proven model

SportsLine's projection model, which is on a 35-29 roll on top-rated MLB money-line picks, has locked in its MLB picks for the Seattle Mariners vs. Toronto Blue Jays matchup on Monday at Rogers Centre in Toronto

ByUpdated: Oct 13, 2025 8:37PM UTC . 2 min read

The Toronto Blue Jays will look to even their best-of-seven American League Championship Series when they battle the Seattle Mariners in Game 2 on Monday. Seattle opened the ALCS with a 3-1 victory on Sunday night. The Mariners (90-72), who won the AL West, are 41-43 on the road this season, including the postseason. The Blue Jays (94-68), who won the AL East, are 56-28 on their home field in 2025. Shortstop Bo Bichette (knee) is not expected to play for the Blue Jays.

First pitch from Rogers Centre in Toronto is set for 5:03 p.m. ET. The Blue Jays have won six of the past nine meetings with the Mariners. Toronto is a -123 favorite on the money line (risk $123 to win $100) in the latest Mariners vs. Blue Jays odds from DraftKings Sportsbook, with Seattle a +103 underdog (risk $100 to win $103), while the total number of runs Vegas thinks will be scored, or the over/under, is 7 in the latest MLB odds. 

Before you make any Mariners vs. Blue Jays picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times.  It enters the 2025 MLB playoffs a profitable 35-29  on top-rated MLB money-line picks this season. It has excelled making home run prop picks this season, returning nearly 30 units of profit. Anybody following could have seen strong returns!

The model has simulated Mariners vs. Blue Jays 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!

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Daniel Kohn

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