LSU vs. Missouri odds, line, spread: Proven model reveals college basketball picks, predictions for March 10, 2022

A 2022 SEC Tournament battle is on tap between the LSU Tigers and the Missouri Tigers at 2:30 p.m. ET on Thursday at Amalie Arena. Missouri is 12-20 while LSU is 21-10. LSU is ranked fifth in the SEC; Mizzou is ranked 12th. 

The Tigers are favored by 10.5 points in the latest LSU vs. Missouri odds from Caesars Sportsbook, while the over-under is set at 133.5. Before you make any Missouri vs. LSU picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of almost $1,600 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated LSU vs. Missouri 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins LSU vs. Missouri? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.