LSU vs. Houston prediction, odds, time: 2025 Texas Bowl picks from proven model

The 2025-26 college football bowl schedule features eight games on Saturday, with the final matchup being the 2025 Kinder's Texas Bowl between LSU and No. 21 Houston. The Tigers (7-5) are coming off a 17-13 defeat to Oklahoma and will be coached by interim, Frank Wilson. The Cougars (9-3) have alternated wins and losses over their last five and are coming off a 31-24 victory over Baylor.

Kickoff is at 9:15 p.m. ET from NRG Stadium in Houston. The Cougars are 2.5-point favorites in the latest Houston vs. LSU odds, while the over/under is 41.5.

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Before making any LSU vs. Houston picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times, and it is profitable on its top-rated money-line picks since the beginning of the 2024 season. Anyone following could have seen impressive returns.

The model has simulated Houston vs. LSU 10,000 times and the results are in. We can tell you that the model is going Over, and it also says one side of the spread hits well over 70% of the time!

So who wins LSU vs. Houston, and which side of the spread hits well over 70% of the time? Join SportsLine right now to see which side of the Houston vs. LSU spread you need to jump on, all from the computer model that has crushed its college football picks!

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