The Louisville Cardinals look to continue their dominance in the series when they host the Murray State Racers on Thursday. Louisville (1-0) has won the last six meetings between the schools and is 14-6 all-time against Murray State. The Racers (1-0) last defeated the Cardinals in 1984. Kickoff at Cardinal Stadium is set for 7:30 p.m. ET. The Cardinals are 43.5-point favorites in the latest Louisville vs. Murray State odds, while the over/under is 55.5 (see up-to-date odds for every game this week on our college football odds page).

Before you make any Murray State vs. Louisville picks or any other college football predictions, you NEED to see which side Micah Roberts is on. 

Roberts has worked in the Las Vegas sportsbook industry for more than 20 years, including a 13-year run as Station Casinos' book director. Armed with an elaborate network of sources, Roberts has unmatched info in multiple sports. He's also off to an incredible 7-2 start on against-the-spread college football picks this season! Anyone who has followed him is WAY UP.

Roberts knows Louisville has had its way with Murray State during the winning streak, defeating the Racers by at least 24 points in five of the six games. The Cardinals have outscored Murray State 317-60 in those six meetings, racking up at least 55 points on four occasions. Louisville, which has won five straight contests at home, opened the season with a 39-34 triumph over Georgia Tech in which it erased a 15-point halftime deficit by scoring 26 consecutive points in the second half.

The expert also knows Murray State produced five touchdowns as it kicked off the campaign with a 41-10 home victory against Presbyterian. Wide receiver Taylor Shields made only two catches in the win, but both were for touchdowns. The redshirt junior also hauled in a scoring pass in each of his final two contests last season.

Now, Roberts has locked in another confident against-the-spread pick for Louisville vs. Murray State. We can tell you he's leaning Over the total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Louisville vs. Murray State on Thursday, and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Murray State vs. Louisville spread to jump on, all from the expert who's an outstanding 7-2 on against-the-spread college football picks this season!