Knicks vs. 76ers prediction, odds, line: Proven model reveals 2026 NBA picks for Jan. 24

Eastern Conference powers meet on Saturday afternoon when the New York Knicks travel to take on the Philadelphia 76ers. New York is 27-18 and is coming in off a laugher against the Nets as the Knicks won 120-66. The Sixers are 24-19 and have lost three of their last five. 

Tipoff is at 3 p.m. ET from the Xfinity Mobile Arena in New York. The latest Knicks vs. 76ers odds list Philadelphia as the 1.5-point favorite, while the over/under is 227.5.

Before making any Knicks vs. 76ers picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 14 of the 2025-26 NBA season on a sizzling 35-15 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated this matchup 10,000 times and the results are in. The model is going Over on the point total, and it also says one side of the spread hits in nearly 70% of the simulations.

Who wins Knicks vs. Sixers, and which side of the spread hits nearly 70% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 35-15 roll on top-rated NBA spread picks!