Kentucky vs. St. John's odds, prediction: 2025 CBS Sports Classic picks from proven model

The 2025 CBS Sports Classic tips on Saturday when the No. 22 St. John's Red Storm take on the Kentucky Wildcats. Kentucky is 7-4 on the season, while St. John's is 7-3.

Tipoff from State Farm Arena in Atlanta is set for 12:30 p.m. ET. The Red Storm are 2.5-point favorites and the over/under is 155.5 in the latest Kentucky vs. St. John's odds. Be sure to watch on CBS or stream on Paramount+, where you can get a free 7-day trial. Sign up here.

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Before making any Kentucky vs. St. John's picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and enters Week 7 on a sizzling 7-1 run on top-ranked over/under picks. Anyone following could have seen HUGE returns!

The model has simulated this matchup 10,000 times and the results are in. We can tell you that the model is going Over, and it also says one side of the spread hits in nearly 60% of simulations!

So who wins St. John's vs. Kentucky, and which side hits in nearly 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!

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