Kentucky vs. Florida odds, prediction: 2026 Southeastern Conference men's college basketball picks from proven model

Two of the top three teams in the Southeastern Conference face off when the 25th-ranked Kentucky Wildcats meet the No. 14 Florida Gators on Saturday. Kentucky defeated Tennessee 74-71 on Feb. 7, while Florida rolled to an 86-66 win at Georgia on Wednesday. The Wildcats (17-7, 8-3 SEC), who are tied for second in the SEC with Arkansas, are 3-3 on the road this season. The Gators (18-6, 9-2 SEC), who lead the conference, are 10-1 on their home court.

Tipoff from the Stephen C. O'Connell Center in Gainesville, Fla., is set for 3 p.m. ET. Kentucky leads the all-time series 111-42, including a 41-26 edge in games played at Gainesville. Florida is a 12.5-point favorite in the latest Kentucky vs. Florida odds from DraftKings Sportsbook, while the over/under for total points scored is 152.5. 

Before making any Kentucky vs. Florida picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 15 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 11-5 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Kentucky vs. Florida 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits well over 60% of the time!

So who wins Kentucky vs. Florida, and which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!