The New Orleans Saints will take on the Jacksonville Jaguars on Thursday Night Football. The Saints (3-3), who have dropped three of their last four, were beaten 20-13 at Houston last Sunday. The Jaguars (4-2), meanwhile, have been red hot and won three in a row. They completed a season sweep of the Indianapolis Colts last Sunday with a 37-20 win, but may be without starting quarterback Trevor Lawrence, who injured his left knee in that game and is questionable.

The game will kick off at 8:15 p.m. ET. New Orleans is a 2.5-point favorite in the latest Jaguars vs. Saints odds, while the over/under for total points scored is 40.5. Before you make any Jaguars vs. Saints picks of your own, you NEED to see what SportsLine NFL expert Larry Hartstein has to say.

A veteran sportswriter whose work appears periodically in The New York Times and Los Angeles Times, Mike Tierney has covered the NFL for decades and reported from seven Super Bowls. He is coming off a typically strong 2022 NFL season in which he went 68-54-6, returning $815 to $100 players.

In addition, he is an amazing 35-16 on his last 51 picks in games involving the Jaguars, returning $1,773! Anyone who has followed him is WAY UP!

Tierney knows New Orleans is led by quarterback Derek Carr, who completed 32 of 50 passes for 353 yards and one touchdown in last Sunday's loss to the Texans. He also knows after starting the season 1-2, Jacksonville has won three consecutive games, including twice in London. A major reason for that success has been running back Travis Etienne, who has scored two touchdowns in back-to-back games.

Now Tierney has locked in on Jaguars vs. Saints. We can tell you he's leaning Under the point total and he's found a critical x-factor that has him jumping all over one side of the spread! You NEED to see his analysis before locking in any Jaguars vs. Saints picks of your own.

Who wins Jaguars vs. Saints on Thursday Night Football? And what critical X-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the spread you need to jump on NOW, all from the expert on an OUTSTANDING 35-16 run on picks involving the Jaguars!