A Big 12 battle is on tap between the Iowa State Cyclones and the No. 17 Baylor Bears at noon ET on Saturday at Jack Trice Stadium. Iowa State will be looking to stay unbeaten after picking up a 43-10 win over Ohio last week. The Cyclones are favored by 2.5 points in the latest Iowa State vs. Baylor odds from Caesars Sportsbook, while the over/under is set at 45. 

Before you make any Baylor vs. Iowa State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 4 of the 2022 college football season on a 51-43 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has simulated Iowa State vs. Baylor 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits more than 50% of the time. You absolutely need to see it before locking in your own picks.

So who wins Iowa State vs. Baylor? And which side of the spread hits more than 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.