Indiana vs. Nebraska odds, prediction: 2026 men's college basketball picks for Jan. 10 from proven model

The Big Ten schedule gets underway on Saturday with a matchup of conference title contenders as the 10th-ranked Nebraska Cornhuskers travel to take on the Indiana Hoosiers. Nebraska is off to a perfect 15-0 start and is 4-0 in Big Ten play. Indiana is 12-3 (3-1 Big Ten).

Tipoff is at noon ET from Assembly Hall. The Hoosiers are 4.5-point favorites in the latest Indiana vs. Nebraska odds, while the over/under is 149.5. 

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Before making any Indiana vs. Nebraska picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and enters Week 10 on a sizzling 9-1 run on top-ranked over/under picks dating back to last year. Anyone following could have seen HUGE returns!

The model has simulated this matchup 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits more than 50% of the time!

So who wins Indiana vs. Nebraska, and which side of the spread hits more than 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!

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