Hofstra vs. No. 22 Duke odds, line: Model reveals college basketball picks for matchup on Dec. 12, 2023

The No. 22 Duke Blue Devils (6-3) are hosting the Hofstra Pride (6-3) in a non-conference showdown on Tuesday at 7 p.m. ET from Cameron Indoor Stadium in Durham. The Blue Devils are 15.5-point favorites in the latest Hofstra vs. Duke odds from SportsLine consensus, while the over/under for total points scored is 144 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Hofstra vs. Duke picks, you need to check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters Week 6 of the 2023-24 season on a 99-62 roll on all top-rated college basketball picks dating back to last season, returning more than $2,000 for $100 players. It is also off to an 11-3 start on top-rated spread picks this season. Anyone following has seen HUGE returns!

The model knows Duke sophomore center Kyle Filipowski is a versatile player on both ends of the floor. Filipowski has great footwork down low, averaging a team-high 17.3 points with 8.9 rebounds per game. On Nov. 24 against Southern Indiana, the New York native totaled 21 points, 14 rebounds and three blocks.

The model also knows Hofstra senior guard Tyler Thomas has been the No. 1 offensive playmaker. Thomas has the skillset to get a bucket from all three levels, putting up a team-best 23.6 points along with 4.9 rebounds and 3.1 assists per contest. He's scored 25-plus points in four of his last five games. On Saturday, Thomas logged 29 points and four boards.

Now, the model has set its sights on Hofstra vs. Duke. We can tell you the model is leaning Over on the point total, and it also says one side of the spread hits more than 60% of the time! You ABSOLUTELY need to see the model before locking in any college basketball picks.

Who wins Hofstra vs. Duke, and which side of the spread hits more than 60% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from that's on a 99-62 roll on top-rated college basketball picks!