Guardians vs. Yankees odds, lines: Advanced computer model reveals picks for April 12, 2023, matchup

The New York Yankees (7-4) will try to win their fourth straight series when they face the Cleveland Guardians (7-5) in a series finale on Wednesday afternoon. Cleveland opened the series with a 3-2 win on Monday, but New York responded with an 11-2 win on Tuesday. This series is a rematch of last year's American League Division Series, when the Yankees advanced with a win in Game 5. 

The game is slated to begin at 1:10 p.m. ET from Progressive Field in Cleveland. The Yankees are -120 on the money line (risk $120 to win $100) in the latest Guardians vs. Yankees odds from Caesars Sportsbook, while the over/under for total runs scored is 9.5 (see the latest lines for every game on our MLB odds page).

Before making any Yankees vs. Guardians picks, you NEED to see the latest MLB predictions from the SportsLine Projection Model.

This model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons, and it finished the 2022 MLB season on a 20-14 roll. Anybody who has followed it has seen profitable returns!

The model knows Guardians second baseman Andres Gimenez has already racked up 16 hits through his first 48 at-bats. He is batting .333 with 14 runs and five RBI, hitting one home run as well. Left fielder Steven Kwan is hitting at a .280 clip and has driven in eight runs, recording five multi-hit games already this season. 

The model also knows New York exploded for 11 runs on Tuesday and has already won three straight series to open the season. Star outfielder Aaron Judge, who is the reigning AL MVP, has hit four home runs, driven in seven runs and is batting .341 through his first 41 at-bats. Second baseman Gleyber Torres is hitting .371 and has homered twice. 

Now, it has set its sights on Guardians vs. Yankees We can tell you the model is leaning Under on the total, projecting 9.4 combined runs, and it also says one side of the money line has all the value! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So who wins Yankees vs. Guardians? And which side of the money line has all the value? ... Join SportsLine right now to find out which side of the Guardians vs. Yankees money line you should be all over on Wednesday, all from the model that finished on a 20-14 roll on top-rated MLB money-line picks in 2022!