Grand Canyon vs. Maryland odds, prediction: 2025 NCAA Tournament picks from proven model

The No. 4 seed Maryland Terrapins and the No. 13 seed Grand Canyon Antelopes match up in the first round of the 2025 NCAA Tournament on Friday. The Terrapins finished the regular season with a 25-8 record, winning four of their last five games. On the flip side, Grand Canyon went 26-7 and heads into the tournament on a three-game win streak. 

Tipoff from the University of Climate Pledge Arena in Seattle, Wash., is set for 4:35 p.m. ET. Maryland is a 10.5-point favorite in the latest Grand Canyon vs. Maryland odds from SportsLine consensus, while the over/under for total points scored is 149.5.

Before making any Grand Canyon vs. Maryland picks, check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division 1 college basketball game 10,000 times. It enters the 2025 NCAA Tournament on a 228-166 roll (+2025) on all top-rated college basketball picks dating back to 2023. This model has also produced brackets that have beaten over 91% of CBS Sports entries in four of the last six tournaments and nailed 24 first-round upsets by double-digit seeds! Anyone following could have seen HUGE returns!

The model has simulated Grand Canyon vs. Maryland 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread cashes in well over 60% of simulations!

So who wins Grand Canyon vs. Maryland, and which side of the spread cashes in well over 60% of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that is 228-166 (+2025) on top-rated college basketball pick and has nailed 24 double-digit upsets!