Giants vs. Cardinals odds, picks: Advanced computer MLB model releases selections for Sunday Night Baseball matchup

The St. Louis Cardinals and the San Francisco Giants square off in prime time at 7:00 p.m. ET on Sunday. San Francisco is listed as a -135 favorite (risk $135 to win $100) at Caesars Sportsbook, while the Over-Under is set at 7 (see up-to-date odds for every game this week on our MLB odds page). Before making any Giants vs. Cardinals picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times and it is off to a sizzling start to the 2022 season. It's on a 31-19 roll on top-rated MLB money-line picks through five weeks, returning almost $800 for $100 players. Anyone following it has seen HUGE returns!

The model knows the Giants are deploying an elite starting pitcher in Carlos Rodon. The talented left-hander was an All-Star in 2021, posting a 2.37 ERA with 12.6 strikeouts per nine innings. Rodon has been even better this season with a 1.80 ERA in six starts. He has 53 strikeouts in 35 innings, and Rodon has not allowed a home run in 2022.

The model also knows the Cardinals are in a strong position at starting pitcher. Adam Wainwright takes the ball for St. Louis and the three-time All-Star has a 3.18 ERA in six starts this season. Wainwright has elite command, issuing only 2.4 walks per nine innings in his career, and he threw seven shutout innings in this last start. Wainwright also has a 2.25 ERA at home in 2022.

Now, it has set its sights on Giants vs. Cardinals. We can tell you the model is leaning Over the total, and it also says one team has all the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Who wins Giants vs. Cardinals? And which team has all the value on the money line? ... Join SportsLine right now to find out which side of the Giants vs. Cardinals matchup you should be all over Sunday, all from the model on a roll on MLB picks!