FIU vs. Missouri State odds, line: 2025 college football picks for Week 10 predictions from proven model

The Missouri State Bears (4-3) and the FIU Panthers (3-4) square off in a Conference USA showdown on Wednesday evening. The Panthers lost 45-26 to Kennesaw State last week. The Bears, however, have won two straight matchups. In Week 9, Missouri State beat New Mexico State 24-17 in overtime. 

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1 JOIN NOW. 

Kickoff from the Robert W. Plaster Stadium in Springfield, Missouri, is at 8 p.m. ET on CBS Sports Network. The Bears are 3.5-point favorites in the latest FIU vs. Missouri State odds, while the over/under for total points scored is 50.5 via SportsLine consensus.

Before making any FIU vs. Missouri State picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks, and it enters Week 10 on a profitable 47-33 combined run on money-line and over/under picks since the beginning of 2024. Anyone following could have seen impressive returns.

The model has simulated FIU vs. Missouri State 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in nearly 60% of simulations!

So who wins FIU vs. Missouri State, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month at SportsLine for $1 JOIN NOW.