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Fantasy football rankings: 2025 NFL Week 2 projections from proven model that outperformed experts

The SportsLine Projection Model, which simulates every NFL game 10,000 times, has locked in its Week 2 Fantasy football rankings

ByPublished: Sep 14, 2025 12:40PM UTC . 3 min read

The stars played as stars in the opening week with the likes of Josh Allen and Derrick Henry leading their respective positions in yards. While they are must-starts for Week 2 Fantasy football lineups, decisions will have to be made regarding other players. Keon Coleman had the fourth-most receiving yards (110) in Week 1, while RJ Harvey was the top rookie running back with 70 yards. Where do these players, and other surprise standouts like Juwan Johnson and Javonte Williams, fall in the Week 2 Fantasy football rankings?

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One shouldn't panic if early-drafted players underperformed in the opener such as Jahmyr Gibbs or Ja'Marr Chase, as you surely want to still keep them as Week 2 Fantasy football picks. However, there are trends and patterns that one should have gleaned from Week 1 that can help them with their Week 2 Fantasy football strategy. 

Before setting your Fantasy football lineups, you NEED to see the Week 2 Fantasy football rankings from SportsLine's advanced computer model. 

When it comes to ranking players, SportsLine's model beat human experts for the past several seasons, especially when there were big differences in ranking! That could literally be the difference between winning your league or going home empty-handed.

Now the model, which simulates every NFL game 10,000 times, has revealed its latest Week 2 Fantasy football rankings.

One player the model is high on this week: Cardinals receiver Marvin Harrison Jr. And a massive shocker: Chiefs quarterback Patrick Mahomes, a two-time MVP who had 315 total yards and two total touchdowns in Week 1, stumbles big-time and doesn't even crack the top 10 at his position! He's a player to fade this week.

The model is also calling for a SHOCKING tight end you aren't even thinking about to finish in the top 10 of its Week 2 Fantasy football rankings! This pick could be the difference between winning BIG and going home with nothing. You ABSOLUTELY need to see who it is before locking in your lineups.

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW. 

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Ross Kelly

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