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Fantasy football rankings: 2025 NFL Week 12 projections from proven model that outperformed experts

The SportsLine Projection Model, which simulates every NFL game 10,000 times, has locked in its Week 12 Fantasy football rankings

ByPublished: Nov 23, 2025 5:06PM UTC . 3 min read

Seeing how a player has previously performed versus his opponent is Week 12 Fantasy football advice everyone should heed. However, with just three divisional games on the slate, several players will be facing opponents for the first time. Thus, you'll have to rely on other factors when making Fantasy football start-sit decisions and filling out Week 12 Fantasy football lineups. Observing a defense's success, or lack thereof, versus a position is another helpful tool when making picks, especially in a week where the statuses of players like Drake London (knee), Marvin Harrison Jr. (appendectomy), Josh Jacobs (knee) and Aaron Rodgers (wrist) are out. Kenneth Walker III and Xavier Worthy had injury designations coming into the week but are active.

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The Rams have allowed the fewest Fantasy points to running backs as L.A. will take on Tampa on Sunday night. Whether it's Sean Tucker or Rachaad White receiving carries with Bucky Irving (shoulder/foot) still out, should you avoid Bucs backs with Week 12 Fantasy football picks? Meanwhile, the Cowboys give up the most Fantasy points to receivers, making A.J. Brown a bit more attractive part of a Week 12 Fantasy football strategy, despite his own previous comments.

Before setting your Fantasy football lineups, you NEED to see the Week 12 Fantasy football rankings from SportsLine's advanced computer model. 

When it comes to ranking players, SportsLine's model beat human experts for the past several seasons, especially when there were big differences in ranking! That could literally be the difference between winning your league or going home empty-handed.

Now the model, which simulates every NFL game 10,000 times, has revealed its latest Week 12 Fantasy football rankings.

One player the model is high on this week: Jaguars wideout Parker Washington, who sits outside the top 40 receivers in both standard and PPR leagues, and is only being started in 37% of leagues. And a massive shocker: Cowboys QB Dak Prescott, who is the QB8 entering Week 12 and is coming off a four-touchdown game, may not warrant a spot in Week 12 Fantasy football lineups as he sits outside the top 15 in quarterback rankings!

The model is also calling for a SHOCKING quarterback you aren't even thinking about to finish in the top five of its Week 12 Fantasy football rankings! This pick could be the difference between winning BIG and going home with nothing. You ABSOLUTELY need to see who it is before locking in your lineups.

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Ross Kelly
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