Now that you've gone on the clock and made your Fantasy football picks, it's time to select the players who will comprise your Week 1 Fantasy football lineups. It may be as simple as using the first six or seven players who drafted, or you may have identified a plus-matchup which makes someone taken in the later rounds a must-start for your Week 1 Fantasy football picks. Rookie running backs like R.J. Harvey and Kaleb Johnson had mid-round ADPs and are interesting Fantasy football start/sit decisions for their NFL debuts.

A reliable set of Week 1 Fantasy football rankings could make these decisions easier as there's been so much roster turnover, coaching changes and shuffling of depth charts since we last saw meaningful football. Who do the Fantasy football projections see as making an impact in the opening week? Before setting your Week 1 Fantasy football lineups, you NEED to see the Week 1 Fantasy football rankings from SportsLine's advanced computer model. 

When it comes to ranking players, SportsLine's model beat human experts for the past several seasons, especially when there were big differences in ranking! That could literally be the difference between winning your league or going home empty-handed.

Now the model, which simulates every NFL game 10,000 times, has revealed its latest Week 1 Fantasy football rankings.

One player the model is high on this week: Jaguars quarterback Trevor Lawrence. And a massive shocker: Bills running back James Cook, a two-time Pro Bowler who led the NFL with 16 rushing touchdowns last season, stumbles big-time and doesn't even crack the top 10 at his position! He's a player to fade this week.

The model is also calling for a SHOCKING running back you aren't even thinking about to finish in the top 10 of its Week 1 Fantasy football rankings! This pick could be the difference between winning BIG and going home with nothing. You ABSOLUTELY need to see who it is before locking in your lineups.

So who should you start and sit in Week 1? And which surprising running back could lead you to victory? ... Join SportsLine now to get Week 1 Fantasy football rankings for every single position, and see which shocking running back comes out of nowhere to crack the top 10, all from the model that has out-performed experts big-time!