Eagles vs. Lions line, odds: Proven model releases spread pick for 2025 NFL Week 11 matchup on Sunday Night Football

A pair of Super Bowl contenders clash on 'Sunday Night Football' in NFL Week 11 as the Philadelphia Eagles host the Detroit Lions. Philadelphia (7-2) has won three in a row, including a 10-7 victory on Monday night versus Green Bay. Detroit (6-3) has alternated wins and losses over its last four, most recently defeating Washington, 44-22, last week. Philly has won the last two matchups, with the most recent meeting taking place in 2022. Sam LaPorta (back) is out and was recently placed on injured reserve, while the Eagles will welcome back OL Cam Jurgens (knee).

Kickoff from Lincoln Financial Field in Philadelphia is set for 8:20 p.m. ET. Philly is a 2.5-point favorites in the latest Lions vs. Eagles odds, while the over/under for total points scored is 46.5 via SportsLine consensus. Both the spread and the over/under have held steady since first opening. Philly is at -147 on the money line (risk $147 to win $100), while Detroit is at +124 (risk $100 to win $124).

Before making any Eagles vs. Lions picks, or 2025 NFL Week 11 predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 11 on a 47-32 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Lions vs. Eagles on 'Sunday Night Football'.

We can tell you it's leaning Over the point total, but also says that one side of the spread hits in well over 50% of simulations! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Eagles vs. Lions in NFL Week 11, and which side of the spread hits in well over 50% of simulations? ... Join SportsLine RIGHT NOW to see which side of the Lions vs. Eagles line to back, all from the model that has gone 47-32 on top-rated picks since 2024!

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