Duke vs. UConn odds, prediction, time: 2026 NCAA Tournament Elite Eight picks from expert

The last ticket to the Final Four will be punched on Sunday evening as the Duke Blue Devils take on the UConn Huskies in a 2026 Elite Eight matchup in the NCAA Tournament. Duke (35-2), the top seed in the East Region, is coming off a Friday Sweet 16 victory over St. John's. No. 2 UConn (32-5) knocked off Michigan State in the Sweet 16. The Blue Devils hold a 5-4 all-time edge between the programs.

Tipoff is at 5:05 p.m. ET from Capital One Arena in Washington, D.C. The Blue Devils are a 5.5-point favorite in the latest UConn vs. Duke odds from DraftKings Sportsbook, while the over/under for total points scored is 133.5. 

Before making any Duke vs. UConn picks, check out what SportsLine college basketball expert Bob Konarski has to say.

Konarski specializes in college basketball, displaying in-depth knowledge of hundreds of Division I teams. He is a regular presence in the SportsLine Discord, co-hosts a weekly Twitter Spaces with fellow CBB expert Tom Casale and can be seen on the "Early Edge" breaking down his college hoops plays. He entered the second weekend of the NCAA Tournament on a 44-28 run on college basketball picks, returning $1,308 for $100 players. Anyone following could have seen huge returns.

Now Konarski has broken down UConn vs. Duke from every angle and locked in his Elite Eight picks. He's leaning Under on the total, and he's also found a critical X-factor that has him jumping on one side the spread! 

So who covers in Duke vs. UConn, and what critical X-factor do you need to know about? Join SportsLine right now to see which side of the UConn vs. Duke spread you need to jump on, all from the expert on a sizzling 44-28 run on CBB pick!