Duke vs. N.C. State odds, prediction: 2026 Atlantic Coast Conference men's college basketball picks from proven model

The top-ranked Duke Blue Devils look to wrap up the Atlantic Coast Conference regular-season championship when they take on the North Carolina State Wolfpack on Monday night. Duke is coming off a 77-51 win over Virginia on Saturday, while N.C. State dropped a 96-90 decision at Notre Dame that same day. The Blue Devils (27-2, 15-1 ACC), who have won six in a row, are 9-1 on the road this season. The Wolfpack (19-10, 10-6 ACC), who have lost two in a row, are 11-4 on their home floor.

Tip-off from Lenovo Center in Raleigh, N.C., is set for 7 p.m. ET. Duke leads the all-time series 153-105, but the teams have split the last six matchups. Duke is a 9.5-point favorite in the latest Duke vs. N.C. State odds from DraftKings Sportsbook, while the over/under for total points scored is 148.5. 

Before making any Duke vs. N.C. State picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 17 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on an 20-11 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Duke vs. N.C. State 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits in well over 50% of simulations!

So who wins Duke vs. N.C. State, and which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!