Teams trending in opposite directions clash when the Miami Dolphins face the Buffalo Bills in a key AFC East matchup on Thursday Night Football. The Dolphins (0-2), who have had winning records in just five of the past 16 years, are 3-7 on the road since last September. The Bills (2-0), who have won the AFC East in each of the past five seasons, are 9-0 at home since the beginning of last year. Josh Allen is 13-2 in his career versus Miami, including the postseason.

Kickoff from Highmark Stadium in Orchard Park, N.Y., is set for 8:15 p.m. ET. The Dolphins lead the all-time series 62-60-1, but the Bills have won 15 of the last 17 meetings, including six in a row. Buffalo is an 11.5-point favorite in the latest Dolphins vs. Bills odds from SportsLine consensus, while the over/under for total points scored is 50.5. Buffalo is a -826 favorite on the money line (risk $826 to win $100), while Miami is at +550 (risk $100 to win $550).

Before making any Dolphins vs. Bills picks or NFL predictions, you NEED to hear what SportsLine football expert Mike Tierney has to say.

A veteran sportswriter whose work appears periodically in the New York Times and Los Angeles Times, Mike Tierney is 235-189-13 in the NFL the past three seasons, returning $2,505 to $100 players (every bet 1 unit). He hit 61.2 percent of his ATS picks (61-39-3) last season. He is also 26-14-3 (+1072) on his last 43 picks involving Buffalo Bills games. Anyone who has followed him could be WAY up!

Now, Tierney has analyzed Dolphins vs. Bills from every angle and just locked in his picks and predictions.

We can tell you he's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Dolphins vs. Bills on Thursday Night Football? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Dolphins vs. Bills spread to jump on, all from the football expert who was 61-39-3 last season on his NFL picks!