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Dodgers vs. Phillies odds, line, start time, picks, best bets for NLDS Game 2 matchup from proven model

SportsLine's projection model, which is on a 34-29 roll on top-rated MLB money-line picks, has locked in its MLB picks for the Los Angeles Dodgers vs. Philadelphia Phillies matchup on Monday at Citizens Bank Park in Philadelphia

ByPublished: Oct 06, 2025 8:59PM UTC . 2 min read

The Los Angeles Dodgers will look to take a commanding 2-0 lead against the Philadelphia Phillies when they meet in Game 2 of their best-of-five National League Division Series on Monday. Los Angeles earned a 5-3 win in Game 1 on Saturday. The Dodgers (93-69), the third seed and NL West champions, are 42-40 on the road this year, including postseason. The Phillies (96-66), the second seed and NL East champions, are 55-27 on their home field in 2025. The Phillies have won three of the five previous postseason series between the franchises.

First pitch from Citizens Bank Park in Philadelphia is set for 6:08 p.m. ET. The Phillies have won six of the past nine meetings with the Dodgers. Los Angeles is a -116 favorite on the money line (risk $116 to win $100) in the latest Dodgers vs. Phillies odds from DraftKings Sportsbook, with Philly at -104. The total number of runs Vegas thinks will be scored, or the over-under, is 7.5 in the latest MLB odds. 

Before you make any Dodgers vs. Phillies picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times.  It enters the 2025 MLB playoffs a profitable 34-29  on top-rated MLB money-line picks this season. It has excelled making home run prop picks this season, returning more than 35 units of profit. Anybody following could have seen strong returns!

The model has simulated Dodgers vs. Phillies 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!

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Daniel Kohn

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