Cowboys vs. Lions line, odds: Proven model releases spread pick for 2025 NFL Week 14 matchup on Thursday Night Football

Teams battling for a playoff spot meet when the Dallas Cowboys face the Detroit Lions in a key NFC matchup on Thursday Night Football. Dallas is coming off a 31-28 win over the Kansas City Chiefs, while Detroit dropped a 31-24 decision to the Green Bay Packers on Thanksgiving Day. The Cowboys (6-5-1), who have won three in a row, are just 1.5 games behind Philadelphia for the NFC East lead. The Lions (7-5), who have lost three of five, have fallen two games behind Chicago in the NFC North. Detroit veteran wide receiver Amon-Ra St. Brown (ankle) is active, while Cowboys pass rusher Jadeveon Clowney (hamstring) is inactive.

Kickoff from Ford Field in Detroit is set for 8:15 p.m. ET. The Cowboys lead the all-time series 19-13, but the Lions won last year's meeting 47-9, which was Dallas' biggest home defeat since 1988. The Lions are 3.5-point favorites in the latest Cowboys vs. Lions odds, while the over/under for total points scored is 55.5. Detroit is at -181 on the money line (risk $181 to win $100), with Dallas at +151.

Before making any Cowboys vs. Lions picks, or 2025 NFL Week 14 predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model entered Week 14 on a 49-33 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Cowboys vs. Lions.

We can tell you it's leaning Over the point total, but also says that one side of the spread hits in well over 50% of simulations! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Cowboys vs. Lions in NFL Week 14, and which side of the spread hits well over 50% of the time? ... Join SportsLine RIGHT NOW to see which side of the Cowboys vs. Lions line to back, all from the model that has gone 49-33 on top-rated picks since 2024!

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