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NFL teams coming off their first wins of the season face off in a London, England matchup Sunday morning, as Daniel Jones and the Indianapolis Colts take on Marcus Mariota and the Washington Commanders. The Colts (1-2) edged the rival Texans 19-17 in Week 3, while the Commanders upset the Seahawks 33-31 in the first start for Mariota for the injured Jayden Daniels. Each team has a defense that ranks among the bottom of the NFL, so points could be scored across the pond. Claim the latest Polymarket promo code SPORTSLINE to get a $50 trading bonus after a $10 deposit:
Kickoff is set for 9:30 a.m. ET from Tottenham Hotspur Stadium in London. The latest Colts vs. Commanders odds have Indianapolis as 3.5-point favorites. The over/under for total points scored is 47.5. Both teams are 2-1 against the spread so far in 2026.
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