Colorado vs. Michigan State odds, betting lines: 2024 college basketball picks, November 25 best bets by proven model

The Michigan State Spartans will face off against the Colorado Buffaloes at 5 p.m. ET on Monday in the 2024 Maui Invitational. Both teams are off to good starts this season. Michigan State is 4-1 overall, while Colorado is 4-0. The Spartans are favored by 8.5 points in the latest Michigan State vs. Colorado odds via SportsLine consensus, and the over/under is 144.5 points.

Before entering any Michigan State vs. Colorado picks, you'll want to see the NCAA Basketball predictions from the proven computer model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 4 of the 2024-25 season on a 162-118 roll (+1952) on all top-rated college basketball picks dating back to 2023. Anyone following has seen HUGE returns!

The model has simulated Michigan State vs. Colorado 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in nearly 70% of simulations. 

So who wins Michigan State vs. Colorado? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks.