Colorado vs. Georgia Tech prediction, odds, spread, line, start time: Proven expert releases college football picks, best bets, game props for Week 1 matchup at Folsom Field

Year three of the Deion Sanders era at Colorado gets underway on Friday when the Buffaloes host the Georgia Tech Yellow Jackets at Folsom Field. The Buffs are 13-12 under Sanders, and are coming off a 9-4 overall record in 2024. Quarterback Shedeur Sanders and reigning Heisman Trophy winner Travis Hunter have moved on to the NFL, and the Buffs once again underwent a massive amount of roster turnover. Former Liberty quarterback Kaidon Salter won the starting quarterback job for Colorado, beating out heralded freshman Julian Lewis during training camp. Georgia Tech is entering its fourth season under head coach Brent Key, and is coming off a 7-6 season in 2024. The Yellow Jackets return nine starters, including quarterback Haynes King. 

The Yellow Jackets are 3.5-point favorites in the latest Georgia Tech vs. Colorado odds, while the over/under for total points scored is 51.5. Georgia Tech is a -181 (risk $181 to win $100) favorite on the money line, with Colorado listed as a +150 underdog (see up-to-date odds for every game this week on our college football odds page). 

Before you make any Colorado vs. Georgia Tech picks or any other college football predictions, you NEED to see which side proven SportsLine expert Jimmie Kaylor is on. 

Kaylor is an NFL, college football and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor has destroyed the sportsbooks in college football the last two seasons, posting a 235-152-7 record since Week 1 of the 2023 season. His 2024 college football futures picks included Travis Hunter winning the Heisman at 40-1 odds, bringing his net profit up to a whopping 112.82 units ($11,282.50 for a $100 bettor) since joining SportsLine as an expert in 2023.

All of his picks have been featured on his SportsLine expert page or in his weekly bylined articles. Anyone who followed his picks could be way up.

Now, Kaylor has locked in a confident against-the-spread pick for Colorado vs. Georgia Tech in their Week 1 matchup. We can tell you he's leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Colorado vs. Georgia Tech in their Week 1 matchup in Boulder and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the spread to jump on, all from the expert who is 235-152-7, returning $11,282 for $100 bettors, betting on college football since 2023, and find out!

Be sure to follow Jimmie (@jimmiekaylor) on Twitter for notifications about picks changes/updates