College basketball odds, lines, spreads, picks, predictions for Wednesday, Nov. 19: 3-way parlay pays almost 10-1

The 2025-26 college basketball schedule continues on Wednesday, Nov. 19, including two ranked matchups. One is a top-five tilt that has No. 3 UConn Huskies hosting the No. 4 Arizona Wildcats at 7 p.m. ET. Both teams are off to 4-0 starts this year as UConn is favored by 7.5 points per the latest college basketball odds. The other ranked contest sees No. 8 Illinois favored by 3.5 points over No. 11 Alabama as the Tide look to bounce back from a loss to Purdue.

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Before locking in any college basketball bets or parlays, make sure you see what SportsLine's advanced computer model has to say. 

The SportsLine Projection Model simulates every college basketball game 10,000 times and has returned over $2,000 in betting profit for $100 players on its top-rated college basketball picks over the past three-plus seasons. Anyone following could have seen HUGE returns!

One pick we'll give away: The model loves UConn (-7.5) to cover in well over 60% of simulations against Arizona at 7 p.m. ET.

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