College basketball odds, lines, spreads, picks, predictions for Friday, Nov. 7: 3-way parlay pays nearly 6-1

The 2025-26 college basketball schedule continues on Friday, Nov. 7, including nine games involving ranked teams. The action continues all day until the final matchup gets underway at 10:30 p.m. ET. Some college basketball odds of note for Friday include No. 19 Kansas vs. No. 25 North Carolina (-2.5), Georgetown vs. Maryland (-4.5), Valparaiso vs. Kentucky (-32.5) and Detroit vs. Notre Dame (-21.5).

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.

Before locking in any college basketball bets or parlays, make sure you see what SportsLine's advanced computer model has to say. 

The SportsLine Projection Model simulates every college basketball game 10,000 times and has returned over $2,200 in betting profit for $100 players on its top-rated college basketball picks over the past three seasons. Anyone following could have seen HUGE returns!

One pick we'll give away: The model loves George Mason (-11.5) to cover in 70% of simulations against Winthrop at 7 p.m. ET.

The model has also locked in two more strong picks, including a pick in Kansas vs. North Carolina that hits well over 60% of the time! You ABSOLUTELY need to see it right now.

So what are the best bets for Friday college basketball action? ... Join SportsLine now to see who wins and covers every single CBB game this week, all from the model that's coming off a profitable year on top-rated CBB picks!

LIMITED TIME: Use promo code CHAMPIONSHIP to get your first month for $1 JOIN NOW.