Coastal Carolina vs. Louisiana Tech odds, line: 2025 college football picks for Independence Bowl matchup from proven model

The Coastal Carolina Chanticleers meet the Louisiana Tech Bulldogs in the 2025 Independence Bowl on Tuesday afternoon. Coastal Carolina closed out the regular season with a 59-10 loss to James Madison, while Louisiana Tech stopped Missouri State 42-30 on Nov. 29. The Chanticleers (6-6), who finished third in the Sun Belt Conference East Division at 5-3, have lost three in a row. The Bulldogs (7-5), who finished tied for fourth in Conference USA at 5-3, have won two consecutive games.

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Kickoff from Independence Stadium in Shreveport, La., is at 2 p.m. ET. This will be the first meeting between the schools. The Bulldogs are 10.5-point favorites in the latest Coastal Carolina vs. Louisiana Tech odds, while the over/under for total points scored is 50.5 via SportsLine consensus. 

Before making any Coastal Carolina vs. Louisiana Tech picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

The model simulates every FBS game 10,000 times, and it is 31-19 on rated college football money-line picks since the beginning of the 2024 season. 

The model has simulated Coastal Carolina vs. Louisiana Tech 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in nearly 70% of simulations!

So who wins Coastal Carolina vs. Louisiana Tech, and which side of the spread hits nearly 70% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times! 

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