Chiefs vs. Jaguars odds, line, spread: Proven model reveals NFL picks, predictions for Week 10, 2022

Patrick Mahomes has already established himself as one of the top quarterbacks in the NFL, while Trevor Lawrence is looking to do the same in his second season. The two will face off Sunday when the Jacksonville Jaguars (3-6) visit Kansas City (6-2) at 1 p.m. on Paramount+. Both teams are coming off of nail-biting wins, as they both look to establish themselves in the AFC this year. Kansas City is favored by 9.5 points in the latest Chiefs vs. Jaguars odds from Caesars Sportsbook, and the over/under is 51.

Sunday's showdown will be televised on CBS and streamed live in select markets on Paramount+ with their MUST-HAVE Premium plan. Plus, you can watch games on ANY device, which you can try for FREE for 7 days!

Before you make any Jaguars vs. Chiefs picks and predictions, you NEED to see what the SportsLine Projection Model is saying. The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. It enters Week 10 of the 2022 NFL season on an incredible 151-108 run on top-rated NFL picks that dates back to the 2017 season. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, it has simulated Chiefs vs. Jaguars 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in over 50 percent of simulations! You ABSOLUTELY have to see it before locking in your own NFL picks!

Who wins Chiefs vs. Jaguars? And which side of the spread cashes over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks!