Chiefs vs. Giants line, odds: Proven model releases spread pick for 2025 NFL Week 3 Sunday Night Football

The Kansas City Chiefs look to get back on track when they take on the New York Giants on Sunday Night Football. Kansas City fell 20-17 to the Philadelphia Eagles in Week 2, while the New York Giants fell 40-37 in overtime to the Dallas Cowboys. The Chiefs (0-2), the nine-time defending AFC West champions, have not had a losing record since 2012. The Giants (0-2), who have not placed higher than second in the NFC East since 2011, last reached the postseason in 2022.

Kickoff from MetLife Stadium in East Rutherford, N.J., is set for 8:20 p.m. ET. The Chiefs have won the last two meetings with the Giants, but New York is undefeated (7-0) at home, all-time, versus Kansas City. The Chiefs are 6-point favorites in the latest Chiefs vs. Giants odds, while the over/under for total points scored is 44.5. The Chiefs are -319 favorites on the money line (risk $319 to win$100), while the Giants are +255 underdogs (risk $100 to win $255). 

Before making any Chiefs vs. Giants picks or 2025 NFL Week 3 predictions of your own, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model is on a sizzling 37-17 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Chiefs vs. Giants on Sunday Night Football.

We can tell you it's leaning Under the point total, but also says that one side of the spread hits in well over 50% of simulations! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Chiefs vs. Giants in NFL Week 3, and which side of the spread hits in well over 50% of simulations? ... Join SportsLine RIGHT NOW to see which side of the Chiefs vs. Giants line to back, all from the model that has gone 37-17 on top-rated picks since 2024!