The Kansas City Chiefs will try to inch closer to their seventh consecutive AFC West championship when they take on the second-place Los Angeles Chargers on Sunday Night Football. The Chiefs (7-2) could increase their division lead to three games and sweep the season series with Los Angeles with a victory. The Chargers (5-4), meanwhile, will try to close the gap to one game with a win and enhance their chances of making the postseason for the first time in four years. Kansas City defeated Los Angeles 27-24 in Week 2.

Kickoff from SoFi Stadium in Inglewood, California, is set for 8:20 p.m. ET. Kansas City is favored by 5.5 points in the latest Chiefs vs. Chargers odds at Caesars Sportsbook, while the over/under is 52.5. Before making any Chiefs vs. Chargers picks, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 11 of the 2022 NFL season on an incredible 153-108 run on top-rated NFL picks that dates back to the 2017 season. 

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

The model knows Kansas City quarterback Patrick Mahomes passed for 331 yards and four touchdowns in Week 10 against the Jacksonville Jaguars. He has 16 games with four or more touchdown passes, tied with Hall of Famer Dan Marino for most by a quarterback in his first six seasons all-time. Mahomes leads the NFL with 2,936 pass yards and 25 touchdown passes and became the third QB ever with 25 or more touchdown passes in five of his first six seasons.

The model also knows Los Angeles quarterback Justin Herbert has passed for 2,450 yards on 254 of 386 passing (65.8%) with 14 touchdowns versus six interceptions for a rating of 89.0. In the 27-24 loss at Kansas City in September, he completed 33 of 48 passes (68.8%) for 334 yards and three touchdowns.

Now, it has set its sights on Chiefs vs. Chargers on Sunday Night Football. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in over 50% of simulations! You ABSOLUTELY need to see it before locking in any NFL picks.

Who wins Chiefs vs. Chargers on Sunday Night Football? And which side of the spread hits in over 50% of simulations? ... Join SportsLine right now to find out which side of the Chiefs vs. Chargers spread you should be all over, all from the model on a 153-108 roll on NFL picks!