Charleston vs. Hampton odds, spread, prediction: 2026 college basketball picks from proven model

Two Coastal Athletic Association squads going in different directions will meet on Thursday's college basketball schedule as the Charleston Cougars visit the Hampton Pirates. Charleston (19-10, 12-4 CAA) has won three in a row, most recently defeating Monmouth on Feb. 21. Hampton (12-16, 6-9 CAA) has lost each of its last three, including a defeat to Stony Brook on Saturday. Charleston has won each of the six all-time meetings.

Tipoff is at 11 a.m. ET from the Convocation Center in Hampton, Va. The Cougars are 4.5-point favorites in the latest Hampton vs. Charleston odds from DraftKings Sportsbook, while the over/under for total points scored is 140.5.

Before making any Charleston vs. Hampton picks, check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every college basketball game 10,000 times and entered Week 17 on a sizzling 11-1 run on top-ranked over/under picks dating back to last year, and is on a 20-11 run on top-rated CBB side picks. Anyone following could have seen HUGE returns!

The model has simulated Hampton vs. Charleston 10,000 times and the results are in. The model is leaning Over, and it also says one side of the spread hits well over 70% of the time!

So who wins Charleston vs. Hampton, and which side of the spread hits well over 70% of the time? Join SportsLine right now to see which side of the Hampton vs. Charleston spread you need to jump on, all from the computer model that has simulated this matchup 10,000 times!