The Los Angeles Chargers can creep closer to earning their first postseason berth in four years with a victory when they take on the Indianapolis Colts in a key AFC matchup on Monday Night Football. The Chargers (8-6) have been on a roll of late, winning three of their last four games, including a 17-14 win over the Tennessee Titans last Sunday. The Colts (4-9-1) have been dreadful for the latter part of the season, losing four in a row and seven of eight. 

The game from Lucas Oil Stadium in Indianapolis is slated to start at 8:15 p.m. ET. Los Angeles is a 3.5-point favorite in the latest Chargers vs. Colts odds from Caesars Sportsbook, while the over/under for total points scored is 44.5. Before you lock in your Chargers vs. Colts picks or any other NFL predictions, you NEED to see which side R.J. White is on.

White, a Fantasy and gambling editor for CBS Sports, consistently crushes against-the-spread picks and went 445-378-24 on his ATS picks from 2017-21, which returned $2,542 to $100 players. He's also an incredible 22-9-2 on his last 33 against-the-spread picks involving the Chargers, returning $1,193 for $100 bettors.

He's well-known for cashing out big in the Westgate Las Vegas SuperContest twice since 2015. White also cashed big on his NFL futures in 2021, including nailing Jonathan Taylor as the NFL rushing leader at 10-1. Anyone who has followed White is WAY UP!

White knows quarterback Justin Herbert powers the Los Angeles offense. In 14 games this season, Herbert has completed 407 of 603 passes (67.5%) for 4,019 yards and 21 touchdowns with nine interceptions for a rating of 91.5. He has also rushed 46 times for 145 yards (3.2 average) and one explosive play of 23 yards. In the win over Tennessee last week, Herbert completed 28 of 42 passes (66.7%) for 313 yards.

White also knows Indianapolis will turn to third-string quarterback Nick Foles to make his first start of the season. Foles is no stranger to success, helping lead the Philadelphia Eagles to the Super Bowl LII championship in 2017. Foles was named the Super Bowl MVP after completing 28 of 43 passes for 373 yards and three touchdowns with one interception in a 41-33 win over the New England Patriots.  

Now, White has locked in another confident against-the-spread pick for Chargers vs. Colts on Monday Night Football. We can tell you he's leaning Under the total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Chargers vs. Colts on Monday Night Football? And what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the Chargers vs. Colts spread to jump on, all from the expert who's an outstanding 22-9 on Los Angeles picks!