Celtics vs. 76ers odds, line: Proven model reveals picks for NBA first round Game 3 matchup on Friday, April 24

The second-seeded Boston Celtics will look to regain control of the series when they meet the seventh-seeded Philadelphia 76ers in Game 3 of their Eastern Conference first-round playoff matchup on Friday. Philadelphia evened the series at 1-1 with a stunning 111-97 win over Boston on Tuesday. The 76ers (45-37), who finished fourth in the Atlantic Division, are 24-18 at home this season, including playoffs. The Celtics (56-26), who won the Atlantic Division, are 26-15 on the road in 2025-26.

Tipoff from Xfinity Mobile Arena in Philadelphia is set for 7 p.m. ET. The Celtics lead the all-time postseason series 67-51, and have won three of the past four playoff meetings. The Celtics are 8.5-point favorites in the latest Celtics vs. 76ers odds from FanDuel Sportsbook, while the over/under for total points scored is 215.5. 

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SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the first full week of the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Celtics vs. 76ers 10,000 times and the results are in. The model is going Under on the point total, and it also says one side of the spread is the better value!

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