Celtics vs. 76ers odds, line: Proven model reveals NBA picks for first round Game 4 matchup on Sunday, April 26

The Boston Celtics will look for a commanding 3-1 series lead over the Philadelphia 76ers when the two meet in Sunday's Game 4. Boston (56-26), the No. 2 seed in the Eastern Conference of the NBA playoffs 2026, took Game 3 on Friday 108-100 to regain home-court advantage in the series. Philly (45-37), the seventh seed in the East, hasn't dropped back-to-back home games since mid-February. The teams split their four regular-season matchups.

Tipoff is at 7 p.m. ET from Xfinity Mobile Arena in Philadelphia. Boston is a 7.5-point favorite in the latest 76ers vs. Celtics odds from FanDuel Sportsbook, while the over/under for total points scored is 213.5. 

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SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered the first full week of the 2026 NBA playoffs on a sizzling 24-9 roll (73%) on top-rated NBA spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated 76ers vs. Celtics 10,000 times and the results are in. The model is going Under on the point total, and it also says one side of the spread hits in well over 50% of simulations!

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