Cavaliers vs. Pistons odds, line: Proven model reveals picks for NBA matchup on Friday, February 27

Two of the hottest teams in the Eastern Conference clash when the Cleveland Cavaliers battle the Detroit Pistons in a matchup of the top two teams in the NBA's Central Division on Friday. Cleveland, which has won eight of 10, dropped a 118-116 decision at Milwaukee on Wednesday, while Detroit, also 8-2 in its past 10, defeated Oklahoma City 124-116 that same night. The Cavaliers (37-23), the fourth seed in the East, are 17-12 on the road this season. The Pistons (43-14), the top seed in the conference, are 22-7 on their home court. Cleveland could be shorthanded due to injuries to James Harden (broken thumb), Donovan Mitchell (groin) and Max Strus (foot).

Tip-off from Little Caesars Arena in Detroit is set for 7 p.m. ET. The Pistons lead the all-time series 134-109, but the Cavaliers have won 13 of the last 15 meetings. The Pistons are a 7.5-point favorite in the latest Cavaliers vs. Pistons odds from DraftKings Sportsbook, while the over/under for total points scored is 225.5. 

Before making any Cavaliers vs. Pistons picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model entered Week 19 on a sizzling 38-18 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Cavaliers vs. Pistons 10,000 times and the results are in. We can tell you that the model is going Under on the point total, and it also says one side of the spread hits in over 50% of simulations!

Who wins Cavaliers vs. Pistons, and which side of the spread hits over 50% of simulations? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 38-18 roll on top-rated NBA picks!