The St. Louis Cardinals (47-40) and the Pittsburgh Pirates (37-50) link up in their series finale on Wednesday afternoon. The Pirates have won two straight games and are coming off a 1-0 victory over the Cardinals on Tuesday night. Sonny Gray (8-2, 3.36 ERA) gets the nod for St. Louis. Mitch Keller (2-10, 3.90 ERA) takes the hill for the Pirates. 

First pitch is scheduled for 12:35 p.m. ET at PNC Park in Pittsburgh. The Cardinals are the -124 money-line favorites (bet $124 to win $100) in the latest Cardinals vs. Pirates odds, while the Pirates are +104 underdogs (bet $100 to win $104). The over/under for total runs scored is 8 in the latest MLB odds. 

Before you make any Cardinals vs. Pirates picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

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The model has simulated Cardinals vs. Pirates 10,000 times and the results are in. We can tell you the model is going Over on the run total, and it also says one side of the money line has all the value!

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