Bulls vs. Pacers odds, line: Proven model reveals picks for NBA matchup on Wednesday, January 28

NBA Central rivals clash on Wednesday when the Chicago Bulls battle the Indiana Pacers. Chicago is coming off a 129-118 loss to the Los Angeles Lakers on Monday, while Indiana dropped a 132-116 decision at Atlanta that same day. The Bulls (23-23), who have won six of their last 10 games, are 8-13 on the road this season. The Pacers (11-36), who are 2-8 within the division, are 8-16 on their home court. Chicago will be without Tre Jones (hamstring) and Zach Collins (toe).

Tip-off from Gainbridge Fieldhouse in Indianapolis is set for 7 p.m. ET. The Bulls lead the all-time series 107-106, but the Pacers have won both meetings this season. Chicago is a 2-point favorite in the latest Bulls vs. Pacers odds from DraftKings Sportsbook, while the over/under for total points scored is 235.5. 

Before making any Bulls vs. Pacers picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 15 of the 2025-26 NBA season on a sizzling 37-16 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Bulls vs. Pacers 10,000 times and the results are in. We can tell you that the model is going Over on the point total, and it also says one side of the spread hits in well over 50% of simulations!

Who wins Bulls vs. Pacers, and which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 37-16 roll on top-rated NBA picks!