Bucks vs. 76ers odds, line: Proven model reveals picks for NBA matchup on Tuesday, January 27

The shorthanded Milwaukee Bucks take on the Philadelphia 76ers in a key NBA Eastern Conference matchup on Tuesday. Milwaukee, who will be without Giannis Antetokounmpo (calf), are coming off a 102-100 loss to the Denver Nuggets on Friday, while Philadelphia dropped a 130-93 decision at Charlotte on Monday. The Bucks (18-26), who have dropped two in a row, are 9-14 on the road this season. The 76ers (24-21), who are fourth in the Atlantic Division, are 12-13 on their home court. Milwaukee will also be without Kevin Porter Jr. (oblique), while Joel Embiid (knee) is questionable for Philadelphia.

Tipoff from Xfinity Mobile Arena in Philadelphia is set for 8 p.m. ET. The Bucks lead the all-time series 125-107, but the 76ers have won both meetings this season. Philadelphia is a 10.5-point favorite in the latest Bucks vs. 76ers odds from DraftKings Sportsbook, while the over/under for total points scored is 219.5. Before making any Bucks vs. 76ers picks, you NEED to see what the SportsLine Projection Model has to say.

SportsLine's model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past eight-plus seasons. The model enters Week 15 of the 2025-26 NBA season on a sizzling 37-16 roll on top-rated NBA spread picks dating back to last season. Anyone following could have seen HUGE returns!

The model has simulated Bucks vs. 76ers 10,000 times and the results are in. We can tell you that the model is going Over on the point total, and it also says one side of the spread hits in over 60% of simulations!

Who wins Bucks vs. 76ers, and which side of the spread hits over 60% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from the model on a 37-16 roll on top-rated NBA picks!