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Broncos vs. Panthers prediction, odds, line, spread: Proven model reveals NFL picks, best bets for Week 12, 2022

The SportsLine projection model simulated Carolina vs. Denver and released its picks, predictions and best bets for this NFL Week 12 game

By@SportsLineUpdated: Nov 27, 2022 3:49PM UTC . 2 min read

The Week 12 NFL schedule features a rematch of Super Bowl 50 when Russell Wilson and the Denver Broncos (3-7) head east to take on the Carolina Panthers (3-8) on Sunday at Bank of America Stadium in Charlotte. Both teams are coming off disappointing losses with the Broncos falling 22-16 in overtime to the Las Vegas Raiders in a long-running AFC West rivalry, and the Panthers losing 13-3 to Lamar Jackson and the Baltimore Ravens. Denver is 3-7 against the spread, while Carolina is 5-6 ATS in 2022.

Kickoff is at 1 p.m. ET. Denver is favored by 1 point in the latest Broncos vs. Panthers odds from Caesars Sportsbook, and the over/under is set at 36.5 points. Before making any Panthers vs. Broncos picks or predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 of the 2022 NFL season on an incredible 155-109 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

Now, it has simulated Broncos vs. Panthers 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread has ALL the value! You absolutely need to see it before locking in your own picks.

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