Broncos vs. Chiefs prediction, line, odds: Proven model releases 2025 NFL Christmas picks

The final matchup of a 2025 NFL Christmas Day tripleheader pits the Kansas City Chiefs against the Denver Broncos in the 'Thursday Night Football' slot. The Broncos lead both the AFC West and the entire AFC with a 12-3 mark, but still have plenty to play for with the Chargers just one game behind them. Kansas City, meanwhile, has seen its season unravel. The Chiefs are 6-9 and are down to third-string quarterback Chris Oladokun and Shane Buechele, signed off the Buffalo practice squad on Monday, after losing Patrick Mahomes and Gardner Minshew to knee injuries in consecutive weeks. 

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Kickoff is from Kansas City is set for 8:15 p.m. ET. The latest Chiefs vs. Broncos odds list Denver as a 12.5-point favorite, while the over/under is 36.5. Before making any Broncos vs. Chiefs picks, you NEED to see which side the proven SportsLine projection model is on.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 on a 52-37 run on top-rated picks dating back to 2024. Anybody following could have seen HUGE returns!

Now, the model has locked in another confident pick for Broncos vs. Chiefs on Christmas. 

The model is going Over the point total, but also says one side of the spread hits nearly 60% of the time! You ABSOLUTELY NEED to see which side to back before locking in any picks of your own.

So who wins Broncos vs. Chiefs on Christmas, and which side of the spread hits in nearly 60% of simulations? ... Join SportsLine RIGHT NOW to see which side of the Broncos vs. Chiefs line to back, all from the model that is 52-37 on top-rated picks since 2024!

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