The Milwaukee Brewers battle the Chicago Cubs in the first of a five-game series and first game of a day-night doubleheader in a key National League Central matchup on Monday afternoon. The Brewers (78-45), who had their 14-game winning streak stopped on Sunday, are 36-25 on the road this season. The Cubs (70-53), who have won two in a row, are 38-23 on their home field in 2025.

First pitch for Game 1 from Wrigley Field in Chicago is set for 2:20 p.m. ET. The teams have split eight games this season. Chicago is a -128 favorite on the money line (risk $128 to win $100) in the latest Brewers vs. Cubs odds from DraftKings Sportsbook, while the total number of runs Vegas thinks will be scored, or the over-under, is 8.5 in the latest MLB odds. 

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The model has simulated Brewers vs. Cubs 10,000 times and the results are in. We can tell you the model is going Under on the run total, and it also says one side of the money line has all the value!

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