Braves vs. Blue Jays line, odds, start time, spread pick, best bets for April 16 matchup from proven model

The Atlanta Braves meet the Toronto Blue Jays in the third and final game of their interleague series on Wednesday afternoon. The Braves (5-12), who have won three of five, are 2-10 on the road this season. The Blue Jays (10-8), who have lost three of five, are 6-3 on their home field.

First pitch from Rogers Centre in Toronto is set for 1:07 p.m. ET. Atlanta is a -142 favorite on the money line (risk $142 to win $100) in the latest Braves vs. Blue Jays odds from SportsLine consensus, while the total number of runs Vegas thinks will be scored, or the over/under, is 7. 

Before making any Braves vs. Blue Jays picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 4 of the 2025 MLB season on an 8-3 run on top-rated money-line picks (+340). Anybody following could have seen strong returns!

The model knows right-hander Spencer Strider is expected to make his season debut as he returns from an arm injury he suffered last April. He was limited to just nine innings in 2024 before undergoing surgery to repair a damaged ulnar collateral ligament. In 67 career games, including 54 starts, he is 32-10 with a 3.47 ERA with 109 walks and 495 strikeouts. In one career start against the Blue Jays, he is 0-1 with a 1.35 ERA, allowing five hits, one earned run, one walk and 12 strikeouts.  

The model also knows right-hander Chris Bassitt (1-0, 0.98 ERA) is expected to take the mound for Toronto. He is coming off a no-decision in a 4-3 loss at Boston on Thursday. In that game, he pitched 5.2 innings, allowing five hits, one earned run and one walk, while striking out five. In a 3-2 loss to the New York Mets on April 5, he received a no-decision after pitching 6.2 innings, allowing no runs on four hits with nine strikeouts. He has never faced the Braves.

The model has simulated Braves vs. Blue Jays 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value!

Who wins Braves vs. Blue Jays, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on an 8-3 run on top-rated MLB picks!