The No. 21 Notre Dame Fighting Irish (2-2) and the Boise State Broncos (3-1) square off on Saturday afternoon. Boise State has won three straight games, including a 47-14 win over Appalachian State last week. Likewise, Notre Dame has secured two straight wins, with a 56-13 victory over Arkansas on Sept. 27. 

Kickoff from Notre Dame Stadium in Notre Dame, Ind, is at 3:30 p.m. ET. This is the first game in history between these schools. The Fighting Irish are 21-point favorites in the latest Boise State vs. Notre Dame odds, while the over/under for total points scored is 62.5 via SportsLine consensus. 

Before making any Boise State vs. Notre Dame picks, be sure to check out the college football predictions and betting advice from the SportsLine Projection Model.

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The model has simulated Boise State vs. Notre Dame 10,000 times and the results are in. We can tell you that the model is leaning Over, and it also says one side of the spread hits in well over 50% of simulations!

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